Syntheses and Processes

Custom synthesis

• reagents, scaffolds and building blocks
• intermediates and advanced intermediates
• lead compounds
• samples and reference compounds
• metabolites
• analytical standards
• focused libraries

Our lab capacity enables us to respond to inquiries dealing with quantities ranging from mg to hundred g-scales.The scope of our services also includes:

• literature search
• design of new routes of synthesis
• process development and optimization for scale-up
• construction of synthesis full technical package
• analytical development

We are accustomed to studying cases involving a large variety of chemistries. We are true generalists in this field yet with special expertises in phenothiazines, azaindoles and in heterocyclic chemistries which we have also built through our internal R&D programs.
 
Isolation and Characterization of Impurities

According to the type of media in which the impurities have been detected, to their concentrations and according to the requested quantities, Provence Technologies will either proceed with isolation and purification of these impurities or try to enrich them prior to isolation and purification or try to generate more of them via forced degradations or find a chemical pathway to synthesize these impurities.
 
Synthetic process development and optimization

Cutting costs, improving overall yield, finding new synthetic pathways to allow easy transfer to larger scale production are common inquiries sent to Provence Technologies. Click here to read related press release.