This research program was conducted from paper to patent by Provence Technologies.
After 6 years of intensive research Provence Technologies found a new synthetic pathway and developed its chemical process leading to the manufacturing of the purest grade of methylene blue which had never been found before.
Provided the high potential of valuation of this discovery, Provence Technologies filed an international patent in 2006 and one year later created an affiliated company Provepharm SAS
dedicated to develop and market Proveblue™, the patented pharmaceutical grade of methylene blue.
In 2013, Provence Technologies optimized the chemical process of Proveblue™ allowing its cost reduction.